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 Automated speech analysis to differentiate frontal and right anterior temporal lobe atrophy in frontotemporal dementia

 Automated speech analysis to differentiate frontal and right anterior temporal lobe atrophy in frontotemporal dementia - https://www.neurology.org/doi/10.1212/WNL.0000000000213556?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200

Frontotemporal dementia (FTD) includes behavioral-variant FTD (bvFTD) with predominant frontal atrophy and semantic behavioral-variant FTD (sbvFTD) with predominant right anterior temporal lobe (rATL) atrophy. These variants present diagnostic challenges because of overlapping symptoms and neuroanatomy. Accurate differentiation is crucial for clinical trial inclusion targeting TDP-43 proteinopathies. This study investigated whether automated speech analysis can distinguish between FTD-related rATL and frontal atrophy, potentially offering a noninvasive diagnostic tool.

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Automated speech analysis to differentiate frontal and right anterior temporal lobe atrophy in frontotemporal dementia

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